浙江大学奶业科学研究所
反刍动物营养研究室
实验室概况
人才培养
所获奖励
在研项目
学术交流合作

刘红云

博士

副教授

导师类别: 博士生导师

研究方向:泌乳生物学、奶牛泌乳调控

联系方式: Tel 0571-88982965;Fax 0571-88982930;Email hyliu@zju.edu.cn

办公地址:浙大紫金港校区农生组团E座345

个人简介:

  刘红云,1978年10月出生,博士,副教授,博士生导师,现代奶业产业技术体系岗位科学家后备人才,浙江大学求是青年学者,浙江大学“十一五”科技创新十佳新秀,并受浙江大学优秀青年教师资助计划资助。2001年9月至2003年6月,浙江大学攻读硕士学位;2003年9月至2006年6月,浙江大学提前攻读博士学位;2006年7月至2008年8月,浙江大学师资博士后研究;2008年9月-2010年12月,浙江大学讲师;2010年12月至今,浙江大学副教授,研究方向为泌乳生物学及奶牛泌乳调控。已主持完成浙江省科技厅重大专项(优先主题)农业项目、中国博士后科学基金、International foundation for science、浙江省教育厅科研项目、浙江大学青年科研创新专项、浙江大学优秀青年教师资助计划等项目各1项;做为主要执行人,负责了农业部公益性行业科研专项和中德国际科技合作项目各1项。目前主持国家自然科学基金1项,作为国家奶牛产业技术体系岗位科学家团队主要成员,协助岗位科学家负责营养与饲料研究室泌乳生理与调控岗位的具体工作。在国内外学术刊物发表论文40余篇,其中SCI收录论文20余篇,授权发明专利1项,申请发明专利2项。现为《Agricultural Sciences in China》等刊物特邀审稿人,参编高等农业院校教材《养牛学》1部。主要从事泌乳生物学及奶牛泌乳调控研究,以提高乳品质、奶产量为出发点,从细胞、组织和个体多水平开展基础及应用研究。基础研究方面,利用蛋白质组学、miRNA研究等技术深入开展泌乳生理的机制研究,通过现代营养学理论和技术,探明营养供应模式与乳成分合成分泌的关系及其吸收利用机制,定向调控乳成分;应用研究方面,开发低碳节能饲料资源及功能性产品,探讨氮磷减排的日粮营养调控技术,实现奶牛的高效安全生产。

工作与教育背景:


工作背景

 

 

 

 

 

2010.12-至今

浙江大学

副教授

 

 

2008.09-2010.11

浙江大学

讲师

 

 

2006.07-2008.08

浙江大学

师资博士后

 

 

其中

2011-至今

美国康奈尔大学

访问学者

 

 

2010.07

美国佛蒙特大学

交流访问

 

 

2008.08

德国霍汉哈姆大学

合作研究

教育背景

 

 

 

 

 

2001.09-2006.06

浙江大学

硕博连读

 

 

1997.09-2001.06

山东农业大学

攻读学士学位

 

教学工作:

  1. 动物营养学- 本科生
  2. 动物细胞生物学- 本科生
  3. 草食家畜生产学-本科生

Lactation Biology –硕博生

奖励与荣誉:

  1. 2011年浙江大学首批求是青年学者
  2. 2011年浙江大学“十一五”科技创新十佳新秀奖
  3. 2011年国家奶牛产业技术体系岗位科学家后备人才
  4. 2010年国家留学基金委全额资助
  5. 2009年度浙江大学院级先进工作者
  6. 2007年度浙江大学优秀青年教师资助计划
  7. 2007年度浙江省自然科学优秀论文二等奖
  8. 2006年度浙江省优秀毕业生

 

研究项目:


项目名称

项目性质及来源

项目经费
(元)

本人
排序

起止年月

奶牛乳腺细胞葡萄糖摄取机制及其对乳成分合成的影响研究

国家自然科学基金

20万

1

2010.01-2012.12

奶牛过瘤胃保护功能性氨基酸的研制及其应用示范

浙江省科技厅重大项目

80 万

1

2008.07-2011.12

Molecular and cellular mechanisms for regulation of milk composition by glucose in mammary epithelial cells

International foundation for science

1万USD

1

2008.04-2010.12

过瘤胃保护GABA对奶牛泌乳性能及其健康状况的影响研究

浙江大学青年科研创新专项

5万

1

2010.01-2010.12

葡萄糖对奶牛乳腺细胞乳蛋白合成调控机理的研究

博士后科研基金

3万

1

2006.10-2008.06

葡萄糖调控乳腺养分合成的细胞分子机制研究

浙江大学优秀青年教师资助计划

10万

1

2007.10-2009.10

蛋氨酸、赖氨酸配比及其二肽对奶牛乳蛋白合成的影响

浙江省教育厅科研项目

1万

1

2007.12-2009.12

奶牛用蛋白饲料的开发研究

企业委托

110万

2

2009.09- 2011.08

南方地区饲料资源的高效利用技术与推广应用

农业部公益性行业基金项目

122万

2

2007.01-2010.12

现代农业(奶牛)产业体系岗位科学家经费

农业部

400万

3

2011.01-2015.12

体细胞诱导的胚胎生殖干细胞增殖和分化机制的研究

国家自然科学基金

21万

3

2005.01-2007.12

饲料基础数据及配套应用技术研究

国家科技支撑计划

35 万

4

2006.01-2010.12

奶牛营养调控及高效饲养技术研究

国家科技支撑计划

113万

7

2006.01-2010.12

发表论文:
已发表学术论文40余篇,其中SCI收录论文20余篇。

  • Wang HF, Liu HY, Liu JX, Zhao K, Wang WR. Effects of Exogenetic trans-10, cis-12, CLA on Lipids Synthesis in Bovine Mammary Epithelial Cells (BMECs). Revised  Corresponding author
  • Wang DM, Wang C, Liu HY, Liu JX. Effects of rumen-protected gamma-aminobutyric acid on feed intake, performance and antioxidant status in transition cows Animal Feed Science and Technology. Submitted  Corresponding author
  • Wang DM, Wang C, Liu HY, Liu JX. Effect of rumen-protected γ-aminobutyric acid on feed intake and milk performance of early lactating dairy cows. Animal Feed Science and Technology. Revised Corresponding author
  • Zhao K, Liu HY, Wang HF, Zhou MM, Liu JX. Hexokinase 2 involves in the glucose uptake regulated by glucose availability in bovine mammary epithelium. Animal. 2012,6:488-493
  • Zhao K, Liu HY, Zhou MM, Liu JX. Lactogenic hormones regulation of glucose transporters gene expression in bovine mammary epithelial cell. Asian Journal of Chemistry. Accepted
  • Zhou MM, Wu YM, Liu HY, Zhao K, Liu JX. Effects of tripeptides and lactogenic hormones on oligopeptide transporter 2 in bovine mammary gland. Journal of Animal Physiology and Animal Nutrition.2011, 95: 781-789
  • Wang HF, Chen Y, Zhao YN, Liu HY, Liu JX, Makkar HPS, Becker K. Effects of replacing soybean meal by detoxified Jatropha curcas kernel meal in the diet of growing pigs on their growth, serum biochemical parameters and visceral organs. Animal Feed Science and Technology. 2011, 170: 141-146
  • Liu HY, Zhao K, Zhou MM, Wang C, Ye JA, Liu JX. Cytoprotection of vitamin E on hyperthermia-induced damage in bovine mammary epithelial cells. Journal of Thermal Biology. 2010, 35:250-253
  • Liu HY, Zeng WD, Cao AL, ZhangCQ. Follicle-stimulating hormone promotes proliferation of cultured chicken ovarian germ cells through protein kinase A and C activation. Journal of Zhejiang University Science-B. 2010, 11: 952-957
  • Zhao K, Liu HY, Zhou MM, Liu JX. Establishment and characterization of lactating bovine mammary epithelial cell model for milk synthesis study. Cell Biology International. 2010, 34, 717-721  Corresponding author
  • Wang C, Liu HY, Wang YM, Yang ZQ, Liu JX, Wu YM, Yan TH, Ye HW. Effects of dietary supplementation of methionine and lysine on milk production and nitrogen utilization in dairy cows. Journal of dairy science. 2010, 93(8):3661-3670
  • Ye JA, Wang C, Wang HF, Liu HY, Wang YM, Chen B, Liu JX. Effects of pelletizing and supplementary methionine, lysine, and choline on the performance of periparturient dairy cows. Acta Agricultrae Scandinavica, Section A-Animal Science. 2010, 60: 230-238
  • Ye JA, Wang C, Wang HF, Ye HW, Wang BX, Liu HY, Wang YM, Yang ZQ, Liu JX. Milk production and fatty acid profile of dairy cows supplemented with flaxseed oil, soybean oil, or extruded soybeans. Acta Agricultrae Scandinavica, Section A-Animal Science. 2009, 59(2):121-129
  • Liu HY, ZhangCQ. Effects of daidzein on mRNA expression of gonadotropin receptors and P450 aromatase in chicken ovarian follicles. Poultry Science. 2008,87:541-545
  •  Liu HY, Yang JY, Wu HH, Wu YM, Liu JX. Effects of methionine and its ratio to lysine on expression of casein αs1 in cultured bovine mammary epithelial cells. 2007. Journal of Animal and Feed Sciences. 2007, 16 (Suppl.): 330-334
  •  Liu HY,Zhang CQ, Ge CT, Liu JX. Effects of daidzein on mRNA expression of gonadotropin receptors and P450 aromatase in ovarian follicles of white silky fowls. Asian-Australasian Journal of Animal Sciences. 2007, 20: 1827-1831
  •  Wu HH, Yang JY, Zhao K, Liu HY, Wu YM, Liu JX. Effects of methionine-containing dipeptides on casein αs1 expression in bovine mammary epithelial cell. Journal of Animal and Feed Sciences. 2007, 16 (Suppl.): 325-329
  • Mi YL, Zhang CQ, Zeng WD, Liu JX, Liu HY. The Isoflavonoid daidzein attenuated the oxidative damage induced by polychlorinated biphenyls on cultured chicken testicular cells. Poultry Science. 2007, 86: 2008-2012
  • Liu HY, Zhang CQ, Zeng WD. Estrogenic and antioxidant effects of a phytoestrogen daidzein on ovarian germ cells in embryonic chickens. Domestic Animal Endocrinology. 2006, 31: 258–268
  •  Liu HY, Zhang CQ. Ginsenosides promote proliferation of cultured ovarian germ cells involving protein kinase C-mediated system in embryonic chickens. Asian-Australasian Journal of Animal Sciences. 2006, 19: 958-963
  • Tang XY, Zhang CQ, Zeng WD, Mi YL, Liu HY. Proliferating effects of flavonoids daidzein and quercetin on cultured chicken primordial germ cells through antioxidant action. Cell Biology International. 2006, 30: 445-451
  •  Liu HY, Zhang CQ, Tang XY, Zeng WD, Mi YL. Stimulating effects of androgen on proliferation of cultured ovarian germ cells through androgenic and estrogenic actions in embryonic chickens. Domestic Animal Endocrinology. 2005, 28: 451- 462
  • Tong FD, Liu HY, Wang Q. Molecular cloning of insulin-like growth factor-Ⅰfrom triangular bream (Megalobrama terminalis). Fish Physiology and Biochemistry,2003, 29: 91- 95
  •  Liu HY, Zhou CQ, Zeng WD, Zhang CQ. Effects of daidzein on follicle development and mRNA expression of P450arom in ovarian follicles of Isa hens. Chinese Journal of Animal Science. 2010, 46(17): 22-24 (in Chinese with English abstract)
  • Liu HY, Zhang CQ. Endocrine regulation of the hypothalamus-pituitary-gonadal axis in avians. Chinese Journal of Veterinary Medicine. 2006, 42: 41-43 (in Chinese with English abstract)
  •  Liu HY, Wang DM,Liu JX. 2010. Research advance of functional amino acids in ruminant. Advanced Research in Feed Nutrition. 181-189  (in Chinese with English abstract)
  • Zhou MM, Wu YM, Liu HY, Zhao K, Liu JX. Role of oligopeptide transporter 2 in bovine mammary gland phenylalanine dieptide uptake. Chinese Journal of Animal Nutrition. 2011,23(8):1303;1308. (in Chinese with English abstract)
  • Wang HF, Liu HY, Yang WR, Liu JX, Yang Zaibin. Effects of exogenetic trans-10, cis-12, CLA on genes expression and protein synthesis of SREBP-1 in bovine mammary epithelial cells. Agricultural Sciences in China. In Press (in Chinese with English abstract)
  • Zhou MM, Liu HY, Zhao K, Wu YM, Liu JX. Absorption and utilization of small peptide in lactating ruminant mammary gland. Chinese Journal of Animal Nutrition. 2011, 23(3): 376-380 (in Chinese with English Abstract)
  • Wang DM, Liu HY, Wang C, Liu JX. Preparation and Stability of Rumen Protected γ-aminobutyric Acid. Chinese Journal of Animal Nutrition. 2010,22(5):1451-1456 (in Chinese with English abstract)
  • Zhao K, Liu HY, Liu JX. Glucose transport and metabolism in lactating bovine mammary gland. China Dairy Cattle. 2009, 170(8): 26-30 (in Chinese with English abstract)
  • Liu HY, Zeng WD, Zhang CQ. Effects of androgen on proliferation of cultured germ cells from embryonic chickens. Chinese Journal of Veterinary Science. 2006, 26: 101-103 (in Chinese with English abstract)
  • Tang XY, Zeng WD, Mi YL, Liu HY, Zhang CQ. Isolation, culture and characterization of chicken primordial germ cells. Chinese Journal of Agricultural Biotechnology. 2006, 14: 174-177 (in Chinese with English abstract)
  •  Liu HY, Zhang CQ. Immunoisolation technology by cell microencapsulation in transplantation medicine. Chinese Journal of Cell Biology. 2004,26: 455-458 (in Chinese with English abstract)
  • Tong FD, Liu HY. Molecular cloning and sequence analysis of IGF-Ⅰfrom triangular bream (Megalobrama terminalis). Agricultural Sciences in China. 2004, 3: 700-706 (in Chinese with English abstract)
  • Tong FD, Liu HY. Molecular cloning and sequence analysis of IGF-Ⅰfrom Triangular Bream (Megalobrama terminalis). Scientia Agricultura Sinica.2004, 37:1564-1570 (in English with Chinese abstract)
  • Tong FD, Liu HY. Molecular cloning and sequence analysis of IGF-Ⅰ from Triangular Bream (Megalobrama terminalis). Agricultural Sciences in China. 2004, 3: 700-706 (in Chinese with English abstract)
Liu HY, Tong FD, Li YM, Hu FL. The effects of temperature and storage time on water-soluble proteins in royal jelly. Food and Fermentation Industries. 2003, 29:1-3 (in Chinese with English abstract?? )

专利成果:

  1. 刘建新, 刘红云, 赵珂. 反刍动物乳腺上皮细胞的分离纯化法和保存方法. 专利号: ZL200810162422.3
  2. 刘红云, 刘建新, 赵珂. 反刍动物乳腺上皮细胞的保持方法. 申请号:201010162042.7
  3. 刘红云, 刘建新, 王迪明. 过瘤胃GABA奶牛精料. 申请号:201110189305.8

 

 

 

学术交流(讲座报告):

报 告 名 称

报 告
性 质

会 议 名 称

报 告
时 间

功能性氨基酸在反刍动物营养总的研究进展

特邀主题报告

全国饲料营养学术研讨会

201010

Major advances in biosynthesis of milk protein and dietary supply strategies to improve its synthesis in dairy cattle

特邀主题报告

The 2nd International Symposium on Dairy Cow Nutrition and Milk Quality

201105

 

 

 

 

 

  • Li Zhen, Liu HY, Liu JX. Expression profiles of microRNAs from non- and lactating bovine mammary glands. ADSA-CSAS-ASAS Joint Annual Meeting Proceedings. July. 2011. New Orleans, American
  •  Liu HY, Zhou MM, Liu JX. Major advances in biosynthesis of milk protein and dietary supply strategies to improve its synthesis in dairy cattle. 2nd International Symposium on Dairy Cow Nutrition and Milk Quality. May. 2011. Beijing, China. (Invited speaker)
  • Liu HY, Wang DM,Liu JX. 2010. Research advance of functional amino acids in ruminant. Advanced Research in Feed Nutrition. 6th National Symposium on Feed Nutrition. October. 2010. Yangling, China. (Invited speaker)
  •  Zhao K, Liu HY, Zhou MM, Liu JX. Effects of lactogenic hormones on gene expression of GLUT1 and GLUT8 in lactating bovine mammary epithelial cells. 6th National Symposium on Feed Nutrition. October. 2010. Yangling, China
  •  Zhao K, Liu HY, Liu JX. Insulin stimulates glucose uptake by regulating cell viability and expression of GLUT8 gene in bovine mammary epithelial cells. ADSA-CSAS-ASAS Joint Annual Meeting Proceedings. July. 2010. Denver, American
  •  Chen Y, Liu JX, Liu HY, Makkar HPS, Becker K. Nutritional evaluation of kernel meal from non-toxic genotype and of detoxified kernel meal from toxic genotype of Jatropha curcas in rat. ADSA-CSAS-ASAS Joint Annual Meeting Proceedings. July. 2010. Denver, American
  • Wang DM, Liu Z, Yang F, Liu HY, Wang C, Wang YM, Liu JX. Effect of rumen protected γ-aminobutyric acid on performance and health status of early lactating dairy cows. ADSA-CSAS-ASAS Joint Annual Meeting Proceedings. July. 2010. Denver, American
  •  Zhou MM, Liu HY, Wu YM, Liu JX. Effect of oligopeptide and lactogenic hormones on expression of peptide transporter PEPT2 gene in bovine mammary tissues. ADSA-CSAS-ASAS Joint Annual Meeting Proceedings. July. 2009. Montreal, Canada
  •  Zhao K, Liu HY, Liu JX. Prolactin, insulin and cortisone regulate expression of GLUT8 gene in bovine mammary explants. ADSA-CSAS-ASAS Joint Annual Meeting Proceedings. July. 2009. Montreal, Canada
  •  Zhao K, Liu HY, Zhou MM, Liu JX. Establishment and function detection of lactating bovine mammary epithelial cell model. XIIIth AAAP Animal Science Congress Proceedings. Sep. 2008. Ha Noi, Vietnam
  •  Zhou MM, Lai JL, Liu HY, Zhao K, Wu YM, Liu JX. Effects of threonine, phenylalanine and their ratio on expression of αs1 casein gene in cultured mammary gland tissue. XIIIth AAAP Animal Science Congress Proceedings. Sep. 2008. Ha Noi, Vietnam
  •  Liu HY, Zhang CQ. Effects of a phytoestrogen daidzein on laying performance and hierarchical follicles gene expression in White silky fowl (Gallina lanigera). Proceeding of 12th AAAP Animal Science Congress. Sep. 2006. Busan, Korea
  • Zhang CQ, Tang XY, Mi YL, Zeng WD, Liu HY. Regulation of gonadal germ cell development in embryonic chikens. Proceeding of 12th AAAP Animal Science Congress. Sep. 2006. Busan, Korea
  • Liu HY, Zhang CQ. Stimulating effects of follicle-stimulating hormone and androgen on proliferation of cultured ovarian germ cells. The 9th National Conference on Animal Physiology and Biochemistry. Aug. 2006. Guangzhou, China
  • Liu HY, Zhang CQ. Estrogenic and antioxidant effects of a phytoestrogen daidzein on ovarian germ cells in embryonic chickens. The 9th National Conference on Animal Physiology and Biochemistry. Aug. 2006. Guangzhou, China
  •  Liu HY, Zhang CQ. Effects of daidzein on laying performance and follicle development in Isa hens and white silky fowls. The 9th National Conference on Animal Physiology and Biochemistry. Aug. 2006. Guangzhou, China
  • iu HY, Zhang CQ, Liu JX. Regulating effects of hormone on proliferation of cultured ovarian germ cells. Medicinal Cell Biology Congress of Chinese Society for Cell Biology. May 2006. Hangzhou, China
  • Liu HY, Tong FD, Wang Q. The effects of temperature and storage time on water-soluble proteins in royal jelly. The 8th National Conference on Animal Physiology and Biochemistry. Aug. 2004. Changchun, China
Zhang CQ, Mi YL, Liu HY, Tang XY, Zeng WD. Regulation of cultured germ cells in embryonic chickens. The 13th Academic Conference on Animal Anatomy and Tissue Embryology. Aug. 2004. Taiyuan, China